Welcome to the latest Ozgene ARC update! In this edition, we will share updates on the AAALAC application, the movement of strains between animal tiers, and the latest health reports from our new facility. We also invite you to attend our Thursday webinar focusing on the validation and phenotyping of genetically engineered mouse models.

AAALAC update

As we prepare to submit our AAALAC application for the Perth facility by the end of June, we would like to congratulate our sister facility in Indianapolis, along with Ozgene LLC President Joanne Deys and IACUC Chair Dr. Thomas Saunders, on the successful recertification of their full AAALAC accreditation. It is exciting to note that the facility received nine commendations, as we continuously aim to standardise systems and processes across our U.S. and Australian sites. This includes our Geneoz Vivarium Management System, which was described by reviewers as a “detailed, innovative paperless system to improve compliance and animal welfare practices.” We will keep you updated as our own AAALAC application progresses.

Strains moving to tier 2

At Ozgene ARC, we believe that research innovation and ethical responsibility go hand in hand. Guided by the 3R principles—Replacement, Reduction, and Refinement—we assess our colonies regularly to ensure resources are used wisely and aligned with research needs.

Strains moving from Tier 1 to Tier 2:

• K18-hACE2
• NOD
• NODSCID

Strain moving from Tier 3 to Tier 2:

• CBB6F1

We kindly encourage you to plan ahead and notify us if your research requires quantities beyond our current availability. The most up-to-date availability is accessible on our ordering portal, and our team is happy to address any inquiries or scheduling needs.

Webinar | beyond genetics:
Validation and phenotyping of genetically engineered animal models

Join us for an exclusive webinar exploring the critical role of validation in preclinical and translational research using genetically modified mouse models.

📅 April 3, 2025 | 9:00 AM AWST (Perth) | 12 PM AEST (Sydney/Melbourne)

This session explores four levels of validation—genetic, phenotypic, functional, and translational—to enhance the reliability of preclinical research. We will discuss key methodologies, technologies, and real-world case studies.

✔ Genetic Validation – Ensuring precise genetic modifications.
✔ Phenotypic Validation – Linking genetic changes to observable traits.
✔ Functional Validation – Confirming biological or behavioural outcomes.
✔ Translational Relevance – Ensuring models reflect human disease pathways.

Can’t attend live? Register to receive the recording after the session.

New health reports

We are pleased to announce that updated health reports for our mice and rats are now available, following our transition into our new facility at the end of 2024. These reports show our strategic approach to colony management, as our stock mouse colonies are now housed across multiple vivariums. This distribution minimises risk and ensures continuity of service should a biosecurity event occur in any single area.
The most recent reports can be accessed under the Biosecurity section of our website. If you have any questions or require further assistance, please do not hesitate to contact us.